Category:
Chiral Intermediates
CAS NO:
/
Standard:
In-house Standards,
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Bosentan monohydrate is a specific crystalline form of the endothelin receptor antagonist, primarily synthesized via condensation reactions. Its chemical identity is defined by the molecular formula C21H24N4O5S and CAS number 138769-23-0.
Strictly contraindicated in pregnancy due to teratogenic risks. Requires storage under controlled humidity to maintain monohydrate stability. Mandatory liver function monitoring is essential during therapeutic use.