Category:
Chiral Intermediates
CAS NO:
183133-96-2
Standard:
In-house Standards,
COA,NMR,HPLC,MSDS, ROS,DMF all available. NLT 99.5% HPLC ,Individual impurity <0.5%
Cabazitaxel (CAS 216985-09-4), chemically defined as 7β, 10β-Dimethoxydocetaxel, is a third-generation taxane microtubule stabilizer. Synthesized via specific semi-synthesis from 10-deacetylbaccatin III, its molecular formula is C45H53NO14.
Strictly contraindicated in patients with severe neutropenia or hypersensitivity to polysorbate 80. Requires storage at -20°C under inert atmosphere; handle with PPE due to cytotoxicity risks.