Category:
Active Pharmaceutical Ingredients
CAS NO:
1492-18-8
Standard:
In-house Standards,
Calcium folinate is a calcium salt of leucovorin, serving as an antidote to methotrexate toxicity and enhancing 5-fluorouracil efficacy. Produced via enzymatic conversion of folic acid derivatives, its molecular formula is C20H21CaN7O7 and CAS No. 58-05-9.
Contraindicated in patients with severe renal impairment without dosage adjustment. Store in cool, dry conditions below 25°C protected from light. Strict clinical monitoring required to prevent masking vitamin B12 deficiency symptoms.