Capecitabine is mainly used for advanced breast cancer, colorectal cancer, can be used as a rescue treatment for breast cancer after failure of anthracyclines and taxanes.
*The following content is generated by AI and is for reference only.
Overview
Capecitabine (CAS: 154361-50-9, C15H22FN3O6) is an oral fluoropyrimidine carbamate prodrug. Manufactured via multi-step organic synthesis, it converts to 5-fluorouracil in tumor tissues.
Application
- Oncology: First-line treatment for metastatic breast cancer.
- Gastrointestinal: Adjuvant therapy for Stage III colon cancer.
- Palliative care: Management of refractory colorectal malignancies.
Precautions
Contraindicated in patients with DPD deficiency. Requires strict temperature control at 25°C and protection from moisture during storage. Healthcare personnel must adhere to PPE protocols for handling cytotoxic agents.