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*The following content is generated by AI and is for reference only.
Overview
Cefadroxil Sulfoxide S-isomer is a critical chiral impurity of the cephalosporin antibiotic Cefadroxil. It arises during oxidation processes or storage, requiring rigorous control in pharmaceutical manufacturing. Molecular Formula: C16H17N3O5S2. CAS No.: 84599-56-0. This stereoisomer is distinct from its R-counterpart and serves as a reference standard for purity analysis.
Application
- Quality Control: Used as an analytical reference standard to quantify specific chiral impurities in bulk drug substances.
- R&D: Employed in stability studies to understand degradation pathways of cephalosporins under oxidative stress.
- Regulatory Compliance: Essential for generating data required by ICH Q3A guidelines regarding impurity profiles.
Precautions
- Storage: Maintain at -20°C in airtight containers protected from light and moisture.
- Safety: Handle with appropriate PPE; avoid inhalation or skin contact due to potential sensitization.
- Usage: Strictly for laboratory research and quality testing; not for direct clinical administration.