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*The following content is generated by AI and is for reference only.
Overview
Cefazolin Impurity 7, identified as Cefazolin Trimethylsilyl Ester, is a specialized synthetic intermediate used in pharmaceutical quality control. Its molecular formula is C16H20N4O5S2Si with CAS No. 128953-87-7. This compound is primarily generated during the derivatization process to enhance volatility for gas chromatography analysis of cephalosporin antibiotics.
Application
- Quality Assurance: Serves as a reference standard for detecting and quantifying specific degradation products in raw materials.
- R&D Analysis: Utilized in method development for stability-indicating assays under ICH guidelines.
- Purity Profiling: Enables precise identification of silylated byproducts during manufacturing optimization.
Precautions
- Storage: Must be stored in airtight containers at -20°C to prevent hydrolysis and moisture absorption.
- Safety: Handle in a fume hood wearing appropriate PPE due to potential irritant properties.
- Usage: Strictly for laboratory research; not approved for direct clinical administration or human use.