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*The following content is generated by AI and is for reference only.
Overview
Cefotiam Impurity 9 is a critical degradation product and synthetic intermediate of the third-generation cephalosporin antibiotic Cefotiam. It serves as a reference standard for quality control to ensure pharmaceutical purity. The compound features a specific beta-lactam structure with defined stereochemistry.
Molecular Formula: C18H20N6O5S2
CAS No: 73431-26-0
Application
- Quality Control: Used in HPLC method validation to identify and quantify trace impurities in bulk drug substances.
- R&D: Serves as a structural analog for stability studies during formulation development.
- Regulatory Compliance: Essential for generating data required by FDA and EMA regarding impurity profiles.
Precautions
- Storage: Maintain at -20°C in a desiccated environment to prevent hydrolysis.
- Safety: Handle with PPE; avoid inhalation of dust or skin contact due to potential sensitization.
- Usage: Strictly for research purposes only; not intended for direct clinical administration.