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*The following content is generated by AI and is for reference only.
Overview
Ceftizoxime Impurity 5 is a critical reference standard for pharmaceutical quality control, serving as a degradation product or synthetic byproduct in the production of the third-generation cephalosporin antibiotic. It is chemically identified as N-(2-amino-4-thiazolyl)-2-[(2Z)-2-(2-aminothiazol-4-yl)-2-hydroxyiminoacetyl]amino]-2-carboxyethyl ester. The molecular formula is C14H16N6O4S, and its CAS registry number is 79380-26-8.
Application
- Quality Assurance: Used in HPLC method validation to identify and quantify impurities in Ceftizoxime bulk drug substances.
- R&D: Employed in stability studies to monitor degradation pathways during formulation development.
- Regulatory Compliance: Serves as a certified reference material for regulatory submissions to agencies like the FDA and EMA.
Precautions
- Store in a cool, dry place under inert atmosphere, protected from light and moisture.
- Handle with appropriate PPE to avoid skin contact and inhalation of dust.
- Not intended for direct clinical administration; strictly for laboratory analytical use only.