Category:
Other Specialized Reagents
Standard:
In-house Standards,
Cholesterol tetraethylene glycol amidite is a specialized phosphoramidite reagent derived from plant sources, essential for solid-phase oligonucleotide synthesis. It features a cholesterol moiety linked via a tetraethylene glycol spacer to the amidite functionality, enhancing hydrophobicity and cellular uptake efficiency. The molecular structure facilitates stable conjugation during automated synthesis cycles.
Strictly store under inert atmosphere at -20°C to prevent oxidation. Handle in a fume hood as the compound is moisture-sensitive and potentially irritant. Not approved for direct clinical use without further purification and regulatory validation.