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*The following content is generated by AI and is for reference only.
Overview
Cidofovir is a synthetic nucleotide analog of deoxycytidine monophosphate, primarily synthesized via enzymatic or chemical pathways to inhibit viral DNA polymerase. Its molecular formula is C8H10N5O4P with CAS No. 91464-78-5.
Application
- Virology: Treatment of cytomegalovirus (CMV) retinitis in immunocompromised patients.
- Pharmaceuticals: Active pharmaceutical ingredient (API) for antiviral formulations.
- Research: Tool compound for studying herpesvirus replication mechanisms.
Precautions
Strictly monitor renal function due to nephrotoxicity risks; requires probenecid co-administration. Store in cool, dry conditions away from light to maintain stability.