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Overview
Cidofovir dihydrate is a synthetic nucleotide analog antiviral agent. Its chemical formula is C8H12N5O4P·2H2O with CAS 113867-49-9. Core manufacturing involves phosphonate ester synthesis and hydration.
Application
- Virology: Treatment of CMV retinitis in immunocompromised patients.
- Pharmaceuticals: Investigational use against poxvirus infections.
- Research: Antiviral mechanism studies in laboratory settings.
Precautions
Strict nephrotoxicity monitoring required; co-administer probenecid mandatory. Store at controlled room temperature, protected from moisture to maintain anhydrous stability during handling.