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Overview
Clembastine Hydrogen Fumarate is a first-generation H1 antihistamine produced via condensation of clembastine with fumaric acid. Its molecular formula is C20H24N2O5 (CAS: 689-69-0). This compound serves as the active pharmaceutical ingredient for managing allergic reactions.
Application
- Allergic rhinitis management in seasonal and perennial forms.
- Treatment of urticaria and pruritus associated with skin allergies.
- Adjunct therapy for mild to moderate anaphylactic symptoms.
Precautions
Strictly avoid use in patients with narrow-angle glaucoma or urinary retention. Store in cool, dry conditions below 25°C away from light. Occupational exposure requires PPE to prevent respiratory irritation.