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Overview
Clofarabine is a nucleoside analog chemotherapy agent primarily synthesized via enzymatic or chemical modification of deoxyadenosine. Its molecular formula is C10H12ClN5O4 with CAS No. 129186-73-2.
Application
- Oncology Manufacturing: Production of injectable solutions for relapsed/refractory acute lymphoblastic leukemia (ALL) in pediatric patients.
- Pharmaceutical R&D: Use as a reference standard and active pharmaceutical ingredient (API) for clinical trials targeting hematologic malignancies.
Precautions
Strictly store at controlled room temperature to prevent degradation. Handling requires PPE due to potential cytotoxicity; avoid inhalation or skin contact during industrial processing.