Category:
Chiral Intermediates
CAS NO:
In-house Standards
Standard:
In-house Standards,
Diseases caused by cerebral thrombosis, cerebral arteriosclerosis, post-traumatic brain syndrome, Meniere's syndrome, coronary sclerosis and poor peripheral circulation
Clofibrate is a synthetic fibrate derivative primarily used as a lipid-lowering agent. Its core synthesis involves the esterification of 2-(4-chlorophenoxy)-2-methylpropionic acid with ethanol. The compound features the molecular formula C₁₂H₁₅ClO₃ and carries the CAS registry number 637-80-5.
Strict clinical monitoring is required due to potential hepatotoxicity and myopathy risks. Storage must occur in sealed containers at cool, dry temperatures away from light to prevent hydrolysis. Handling requires appropriate PPE to avoid skin contact and inhalation of dust particles.