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Overview
COBIMETINIB (XL518) is a potent, selective inhibitor of MEK1 and MEK2 enzymes used in targeted oncology therapy. It functions by blocking the MAPK/ERK signaling pathway to suppress tumor growth. Molecular Formula: C26H27N7O; CAS No: 1094449-66-3.
Application
- Oncology research for melanoma treatment protocols.
- Combination therapies with BRAF inhibitors like vemurafenib.
- Preclinical studies on RAS/MAPK pathway activation.
Precautions
Strictly for laboratory use only; not approved for human consumption. Store under inert atmosphere at -20°C to maintain stability. Handle with appropriate PPE due to potential cytotoxicity.