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Overview
Dabigatran Etexilate is a prodrug of dabigatran, a direct thrombin inhibitor. Key chemical parameters include CAS 256822-10-9 and molecular formula C21H26N6O5. Core synthesis involves esterification processes to ensure high purity for pharmaceutical manufacturing.
Application
- Anticoagulant therapy for stroke prevention in atrial fibrillation.
- Prophylaxis of venous thromboembolism post-orthopedic surgery.
- Treatment of deep vein thrombosis and pulmonary embolism.
Precautions
Strictly contraindicated in severe renal impairment and active bleeding. Store in controlled temperature environments (15-30°C) with low humidity to maintain stability. Handle with PPE due to potential irritancy during processing.