Category:
Active Pharmaceutical Ingredients
CAS NO:
960539-70-2
Standard:
ChP,
Research and development(R&D)
Daprodustat is a hypoxia-inducible factor prolyl hydroxylase (HIF-PHD) inhibitor developed for treating anemia associated with chronic kidney disease. Its core process involves inhibiting PHD enzymes to stabilize HIF-1α, thereby stimulating endogenous erythropoietin production. The compound features the molecular formula C20H24N6O3 and CAS number 975637-87-3.
Strictly contraindicated for patients with uncontrolled hypertension or history of thromboembolic events. Requires storage in sealed containers at controlled room temperature away from moisture. Handling must adhere to occupational safety guidelines for novel small molecule inhibitors.