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Overview
DARATUMUMAB is a recombinant human monoclonal antibody targeting CD38. Molecular Formula: C71H109N21O23S; CAS No: 1455864-73-9.
Application
- Hematologic malignancies treatment, specifically multiple myeloma.
- Combination therapy with proteasome inhibitors and immunomodulators.
- Relapsed or refractory disease management in clinical settings.
Precautions
Requires strict cold chain storage at 2°C to 8°C. Infusion reactions are common; premedication is mandatory. Contraindicated in patients with severe hypersensitivity to the active substance.