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Overview
Darifenacin is a potent, selective M3 muscarinic receptor antagonist primarily manufactured via chiral synthesis. It serves as the active pharmaceutical ingredient for treating overactive bladder. Molecular formula: C24H29NO3; CAS No.: 176085-22-8.
Application
- Pharmaceutical Manufacturing: Bulk production of extended-release tablets for urinary incontinence.
- Clinical Research: Used in studies evaluating anticholinergic efficacy on detrusor muscle relaxation.
Precautions
Contraindicated in patients with uncontrolled narrow-angle glaucoma or gastric retention. Store at controlled room temperature (20°C–25°C) in dry conditions to maintain stability and prevent hydrolysis.