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Overview
Darunavir is a potent non-protease inhibitor (PI) used in HIV-1 treatment. Synthesized via advanced chiral catalysis, its molecular formula is C27H37N3O7S with CAS No. 149845-07-6.
Application
- Pharmaceutical Manufacturing: Active Pharmaceutical Ingredient (API) for combination antiretroviral therapies.
- HIV Management: Treatment of multidrug-resistant HIV-1 infection in adults and pediatric patients.
- Research & Development: Preclinical studies for novel antiviral drug formulations.
Precautions
Must be co-administered with low-dose ritonavir or cobicistat as pharmacokinetic boosters. Store at controlled room temperature (20-25°C) in dry conditions away from light to maintain chemical stability.