Category:
Other Antibiotics
CAS NO:
635728-49-3
Standard:
In-house Standards,
-
Darunavir Ethanolate is a crystalline salt form of the HIV-1 protease inhibitor Darunavir, specifically engineered to enhance solubility and bioavailability. Manufactured via controlled ethanolysis of Darunavir free base, this polymorph ensures superior stability for pharmaceutical formulations. The chemical structure corresponds to the molecular formula C27H39N3O7S·C2H5OH with CAS No. 198604-69-8.
Strictly indicated only in combination with ritonavir or cobicistat; contraindicated in severe hepatic impairment. Store under controlled room temperature (20-25°C) in moisture-proof containers to prevent hygroscopic degradation. Handle with appropriate PPE to avoid inhalation or dermal exposure during manufacturing.