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Overview
Dasatinib Anhydrous is a potent, oral bioavailable second-generation tyrosine kinase inhibitor. Manufactured via high-purity crystallization to ensure anhydrous stability, its molecular formula is C21H26N6O3S (CAS 403643-65-8). This form eliminates water of hydration, enhancing shelf life and dosing precision for pharmaceutical synthesis.
Application
- Oncology Manufacturing: Active Pharmaceutical Ingredient (API) production for chronic myeloid leukemia (CML) and acute lymphoblastic leukemia (ALL).
- Research & Development: Preclinical studies targeting BCR-ABL1 mutations and SRC family kinases.
- Quality Control: Reference standard usage in analytical laboratories for potency verification.
Precautions
- Safety: Handle with PPE; avoid inhalation or skin contact due to potential toxicity.
- Storage: Maintain in sealed containers at 2°C–8°C away from moisture to prevent hydrolysis.
- Regulatory: Restricted to licensed medical facilities; not for direct human consumption without formulation.