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Overview
Delta-2-Cefepime Trifluoroacetate is a critical pharmaceutical intermediate used in the semi-synthetic production of cefepime. It serves as the 7-aminocephalosporanic acid (7-ACA) derivative essential for introducing the N-methylpyrrolidine side chain. The molecular formula is typically represented as C19H24N6O5S·CF3COOH, with CAS registration pending specific salt variations. This compound features high purity levels suitable for GMP manufacturing.
Application
- Antibiotic Manufacturing: Primary precursor for synthesizing fourth-generation cephalosporins.
- Quality Control: Reference standard for HPLC assay validation in API batches.
- Research & Development: Used in stability studies and metabolic profiling of beta-lactams.
Precautions
Store under inert atmosphere at temperatures below -20°C to prevent hydrolysis. Personnel must wear appropriate PPE including respirators due to potential respiratory sensitization from trifluoroacetic acid residues. Do not use directly in clinical settings; strictly for industrial synthesis only.