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Overview
Desloratadine is a third-generation antihistamine derived from loratadine via selective metabolism. Produced through advanced catalytic hydrogenation and crystallization, its molecular formula is C16H15ClN2O with CAS number 1948-70-9.
Application
- Allergy pharmaceuticals: Treatment of seasonal and perennial allergic rhinitis.
- Chronic idiopathic urticaria management for symptom relief.
- R&D as a reference standard in analytical quality control labs.
Precautions
Contraindicated in patients with severe renal impairment without dose adjustment. Store in tightly sealed containers at 15-25°C away from light to maintain stability.