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Overview
Dexrazoxane is a cardioprotective iron chelator primarily synthesized via hydrolysis of bis-ethylenediaminetetraacetic acid diethyl ester. Its molecular formula is C19H28N2O8 with CAS No. 76543-08-3.
Application
- Oncology: Mitigating anthracycline-induced cardiotoxicity in breast cancer and sarcoma patients.
- Pharmaceutical Manufacturing: Used as an excipient in IV formulations for chemotherapy protocols.
Precautions
Strictly contraindicated for pediatric patients under six years old due to malignancy risk. Requires storage at controlled room temperature (20°C–25°C) in light-resistant containers to maintain chemical stability.