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Overview
Dexrazoxane Hydrochloride is a cardioprotective agent used to prevent anthracycline-induced cardiotoxicity. The core process involves chelation of intracellular iron to inhibit free radical formation. Its molecular formula is C14H20ClN3O8 and CAS number is 79560-77-5.
Application
- Oncology: Mitigation of heart damage in breast cancer patients receiving doxorubicin.
- Clinical Trials: Adjunct therapy for metastatic breast cancer under strict regulatory protocols.
Precautions
Contraindicated in pediatric patients and those with hypersensitivity. Requires storage at controlled room temperature away from moisture. Strict clinical monitoring is mandatory due to potential myelosuppression risks.