Diclofenac sodium has long been used to treat acute pain and inflammation, and is effective in various acute forms of pain.
Diclofenac sodium was generally well tolerated in clinical trials, with injection-site reactions among the most commonly reported adverse events. Diclofenac sodium is indicated for the treatment of rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis.
Diclofenac sodium is a potent non-steroidal anti-inflammatory drug (NSAID) synthesized via condensation reactions of 2-chlorobenzene with diethylamine. Its molecular formula is C14H10ClNNaO2 and CAS number is 15307-86-5.
Strictly avoid use in patients with active peptic ulcers or severe renal impairment. Store in cool, dry conditions below 25°C away from direct sunlight to prevent hydrolysis. Handle with appropriate PPE to minimize dermal exposure risks.