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Overview
Diethyl (tosyloxy)methylphosphonate is a specialized organophosphorus intermediate primarily utilized in the synthesis of nucleotide analogs. Its core manufacturing process involves the phosphorylation of diethyl methylphosphonate followed by tosylation. Molecular Formula: C14H20O6PS; CAS No: 87599-58-8.
Application
- Veterinary Medicine: Key precursor for antiviral agents targeting viral DNA polymerase.
- Agricultural Chemicals: Synthesis intermediate for specific phosphonate-based herbicides.
- Research: Used in academic studies regarding phosphorus chemistry and drug delivery mechanisms.
Precautions
- Safety: Handle with gloves and eye protection; avoid inhalation of dust or vapors.
- Storage: Store in a cool, dry, well-ventilated area away from oxidizers and moisture.
- Usage: Not approved for direct clinical use; strictly for industrial R&D and bulk synthesis.