*The following content is generated by AI and is for reference only.
Overview
Diethyl(3-pyridinyl)borane (CAS 100592-87-6), also known as 3-(diethylboryl)pyridine, is a specialized organoboron reagent defined by its pyridine-boron linkage. Synthesized via the hydroboration of 3-ethynylpyridine or direct borylation, this compound serves as a crucial intermediate in medicinal chemistry. Its molecular formula is C9H14BN.
Application
- Pharmaceutical synthesis: Acts as a key building block for constructing heterocyclic drug scaffolds.
- Agricultural chemicals: Utilized in developing novel fungicides and herbicides targeting specific enzymes.
- Material science: Employed in the production of advanced ligands for catalytic cross-coupling reactions.
Precautions
This reagent is moisture-sensitive and requires storage under an inert atmosphere at low temperatures. Strict personal protective equipment (PPE) including gloves and goggles is mandatory during handling to prevent skin irritation and inhalation hazards.