Category:
Active Pharmaceutical Ingredients
CAS NO:
139504-50-3
Standard:
in house,
DM-1 (Dolastatin 10 derivative) is a potent cytotoxic agent serving as the payload for antibody-drug conjugates (ADCs). Synthesized via solid-phase peptide synthesis, its core structure features a unique valine-valine-amide linkage. Molecular Formula: C26H40N6O5; CAS No.: 179837-77-1.
Strictly limited to research use; not approved for standalone clinical administration. Requires storage at -20°C under inert atmosphere. Personnel must utilize PPE due to extreme potency and potential neurotoxicity risks during handling.