Category:
Active Pharmaceutical Ingredients
CAS NO:
796073-69-3
Standard:
In-house Standards,
DM4, or Monomethyl Auristatin F (MMAF), is a potent cytotoxic agent derived from dolastatin 10. It serves as the linker-payload component in antibody-drug conjugates (ADCs). The core synthesis involves complex organic coupling to ensure stability. Formula: C29H46N4O5; CAS: 174718-25-5.
Strictly handle under inert atmosphere due to air sensitivity. Store at -20°C protected from light. Personnel must use appropriate PPE as it is highly toxic upon inhalation or skin contact; avoid environmental release.