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Overview
Dolutegravir is a HIV-1 integrase strand transfer inhibitor (INSTI). Its molecular formula is C15H16N4O3 with CAS No. 1248825-49-7.
Application
- Pharmaceutical Manufacturing: Active Pharmaceutical Ingredient (API) for fixed-dose combination antiretroviral tablets.
- Research & Development: Reference standard for stability testing and bioequivalence studies.
Precautions
Requires strict temperature control (20°C–25°C). Contraindicated in patients with hypersensitivity to dolutegravir or severe hepatic impairment when co-administered with certain agents.