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Overview
Doramectin (CAS 117704-25-3) is a macrocyclic lactone antiparasitic agent derived from ivermectin. It features the molecular formula C48H76O14 and is synthesized via fermentation of Streptomyces avermitilis. The compound acts as a potent GABA-gated chloride channel activator.
Application
- Veterinary Medicine: Control of gastrointestinal nematodes, lungworms, and external parasites in cattle and sheep.
- Livestock Production: Treatment of infestations by mites, lice, and flies to improve animal health and growth rates.
Precautions
- Human Safety: Not approved for use in food-producing animals; strict withdrawal periods apply.
- Storage: Store in a cool, dry place away from direct sunlight to maintain chemical stability.