Category:
Intermediates&Fine Chemicals
CAS NO:
60239-18-1
Standard:
USP,
DOTA intermediates are critical macrocyclic precursors used in radiopharmaceutical synthesis. Typically derived from cyclen via alkylation, these compounds feature a tetraazacyclododecane backbone. The standard molecular formula is C16H28N4O8 (CAS 10597-09-4), serving as the chelator core for Gd-based MRI agents.
Storage requires dry, inert atmosphere conditions to prevent hydrolysis. Personnel must use PPE due to potential skin irritation. Strict regulatory compliance is mandatory for clinical-grade batches intended for human administration.