Category:
Other Antibiotics
CAS NO:
77883-43-3
Standard:
In-house Standards,
-
Doxazosin series comprises alpha-1 adrenergic antagonists used for hypertension and BPH. Core synthesis involves nitration and reduction of substituted quinazolines. Key compounds include Doxazosin mesylate (CAS 78624-36-7) with molecular formula C19H20N4O5S.
Contraindicated in severe hepatic impairment; monitor for orthostatic hypotension. Store in sealed containers below 25°C away from light to prevent degradation.