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Overview
Doxercalciferol is a prodrug of 1,25-dihydroxyvitamin D2 used in industrial pharmaceutical synthesis. Manufactured via enzymatic hydroxylation of ergocalciferol, its chemical structure is defined by the molecular formula C28H44O2 and CAS number 120292-72-6.
Application
- Nephrology: Treatment of secondary hyperparathyroidism in chronic kidney disease patients.
- Pharmaceutical Manufacturing: Active pharmaceutical ingredient (API) for oral capsule formulations.
- Veterinary Medicine: Management of mineral metabolism disorders in companion animals.
Precautions
Strictly contraindicated in patients with vitamin D toxicity or hypervitaminosis D. Storage requires controlled room temperature (20-25°C) in light-resistant containers to maintain stability. Handling mandates PPE due to potential sensitization risks.