Category:
Intermediates&Fine Chemicals
CAS NO:
25316-40-9
Standard:
In-house Standards,
Doxorubicin hydrochloride is a potent anthracycline antineoplastic antibiotic widely utilized in oncology. Produced via fermentation of Streptomyces peocolor, it inhibits DNA replication through intercalation and topoisomerase II inhibition. The chemical formula is C27H29NO11·HCl with CAS number 25316-40-9.
Strictly handle as a cytotoxic agent requiring PPE to prevent dermal absorption. Store in tightly sealed containers at 2°C–8°C protected from light. Contraindicated in patients with severe cardiac dysfunction or prior anthracycline exposure due to cumulative cardiotoxicity risks.