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Overview
Duloxetine hydrochloride is a selective serotonin and norepinephrine reuptake inhibitor (SNRI) API. It is synthesized via condensation reactions followed by salt formation with hydrochloric acid. The molecular formula is C18H20ClNO·HCl and CAS number is 149657-75-6.
Application
- Major pharmaceutical manufacturing for treating major depressive disorder.
- Pain management clinics for diabetic peripheral neuropathy.
- Fibromyalgia treatment protocols in specialized hospitals.
Precautions
Contraindicated in patients taking MAOIs. Store in a cool, dry place below 25°C away from light. Use appropriate PPE during handling to avoid inhalation or skin contact.