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Overview
Edoxaban is a direct oral Factor Xa inhibitor used in anticoagulant therapy. The core synthesis involves complex organic coupling reactions to ensure high purity. Key specifications include Molecular Formula: C21H25ClN6O4S and CAS No.: 907483-98-3.
Application
- Prevention of stroke and systemic embolism in non-valvular atrial fibrillation.
- Treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE).
- Post-operative prophylaxis following hip or knee replacement surgery.
Precautions
Contraindicated in patients with active pathological bleeding. Strict storage required at controlled room temperature away from moisture. Avoid use in severe renal impairment without dose adjustment.