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Overview
Emtricitabine is a synthetic nucleoside reverse transcriptase inhibitor (NRTI) used in antiretroviral therapy. Synthesized via enzymatic or chemo-enzymatic routes, its molecular formula is C8H10FN3O3S and CAS number is 142217-69-4.
Application
- HIV-1 treatment in combination with other antiretrovirals
- Pre-exposure prophylaxis (PrEP) for high-risk populations
- Formulation of fixed-dose combination tablets and capsules
Precautions
Contraindicated in severe renal impairment without dose adjustment. Store below 25°C in dry conditions to maintain stability. Strict adherence to PPE is required during industrial handling to prevent dermal exposure.