Category:
Active Pharmaceutical Ingredients
CAS NO:
2118959-55-8
Standard:
In-house Standards,
Ephos (CAS 142079-56-3) is a chiral diphosphine ligand, chemically defined as 1,2-bis(2,5-dimethylphenyl)phosphinoethane. Synthesized via palladium-catalyzed cross-coupling of aryl halides with phosphines, it features a flexible ethylene backbone and bulky methyl-substituted aryl groups. This structure provides high steric hindrance and electronic tunability for asymmetric catalysis.
Store under inert atmosphere (nitrogen or argon) at -20°C to prevent oxidation. Handle in a fume hood using appropriate PPE due to potential toxicity and flammability. Avoid exposure to air and moisture during transfer.