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Overview
Eribulin (E7389) is a synthetic halichondrin B analog used as a microtubule dynamics inhibitor. Its molecular formula is C46H65NO12 with CAS No. 206570-69-2.
Application
- Oncology: Second-line treatment for metastatic breast cancer.
- Oncology: Management of unresectable liposarcoma.
- R&D: Preclinical research on cell cycle arrest mechanisms.
Precautions
Requires strict cytotoxic handling protocols and temperature-controlled storage at -20°C. Contraindicated in severe neutropenia; requires monitoring for peripheral neuropathy during clinical administration.