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Overview
Eribulin mesylate is a synthetic halichondrin B analog used as an antineoplastic agent. The core manufacturing process involves complex total synthesis with rigorous chiral control. Molecular Formula: C25H37NO10S; CAS No.: 698574-65-1.
Application
- Advanced breast cancer treatment in patients previously treated with anthracyclines and taxanes.
- Liposarcoma management for unresectable locally advanced or metastatic cases.
- Chemotherapy regimens requiring microtubule dynamics inhibition mechanisms.
Precautions
Contraindicated during pregnancy due to embryofetal toxicity. Requires strict adherence to PPE protocols for handling hazardous powders. Store at controlled room temperature (20°C to 25°C) protected from light and moisture.