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Overview
Erlotinib is a potent, selective EGFR tyrosine kinase inhibitor. Synthesized via multi-step organic reactions, its molecular formula is C22H23N3O4 with CAS No. 183321-74-6.
Application
- Oncology Manufacturing: Production of pharmaceutical grade APIs for non-small cell lung cancer (NSCLC) and pancreatic cancer therapies.
- Contract Research: Supply for preclinical studies evaluating EGFR mutation responses in tumor models.
- Distribution: Bulk supply to global drug formulators for tablet and capsule formulation.
Precautions
Store at controlled room temperature (20-25°C) in dry, sealed containers. Avoid inhalation or skin contact; use appropriate PPE. Clinical use requires strict monitoring for interstitial lung disease and severe dermatological reactions.