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Overview
Erlotinib Hydrochloride is a potent tyrosine kinase inhibitor targeting the epidermal growth factor receptor (EGFR). Synthesized via specific organic condensation and salt formation, its molecular formula is C22H23ClN4O·HCl with CAS No. 183321-74-6.
Application
- Pharmaceutical Manufacturing: API production for non-small cell lung cancer (NSCLC) therapies.
- Clinical Oncology: Treatment of metastatic NSCLC and pancreatic cancer in combination regimens.
- Research & Development: Tool compound for EGFR signaling pathway studies.
Precautions
Strictly contraindicated for patients with known hypersensitivity. Requires storage below 25°C in dry, light-resistant conditions. Handling mandates PPE to prevent inhalation or dermal exposure due to potential toxicity.