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Overview
Esomeprazole is the S-isomer of omeprazole, a proton pump inhibitor (PPI) synthesized via asymmetric catalysis. It effectively reduces gastric acid secretion. Molecular Formula: C17H18N3O3S; CAS No.: 119943-65-6.
Application
- Gastroenterology: Treatment of GERD and erosive esophagitis.
- Peptic Ulcer Management: Healing duodenal and gastric ulcers.
- H. pylori Eradication: Used in combination antibiotic regimens.
- Acid Hypersecretion Disorders: Control of Zollinger-Ellison syndrome.
Precautions
Contraindicated in patients with hypersensitivity to PPIs. Long-term use requires monitoring for magnesium deficiency and bone fractures. Store in cool, dry conditions below 25°C away from light to maintain stability.