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Overview
Etravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used in antiretroviral therapy. Synthesized via multi-step organic chemistry, its molecular formula is C21H15ClF3N3O2 and CAS number is 204896-73-7.
Application
- HIV-1 treatment for drug-resistant strains.
- Second-line therapy following NNRTI failure.
- Combination regimens with other antiretrovirals.
Precautions
Contraindicated in severe hepatic impairment. Requires storage below 30°C in dry conditions. Monitor for skin rash and hepatotoxicity during clinical use.