Category:
Preclinical Research Services
CAS NO:
870964-67-3
Standard:
ChP,
Evocalcet is a selective calcimimetic agent developed for managing secondary hyperparathyroidism. Its core mechanism involves enhancing the sensitivity of calcium-sensing receptors on parathyroid glands to extracellular calcium, thereby suppressing parathyroid hormone secretion. The chemical structure corresponds to the molecular formula C21H25F4N3O2, with CAS number 850697-83-5.
Clinical use requires strict monitoring of serum calcium and phosphate levels to prevent hypocalcemia. Patients must avoid concomitant administration with strong CYP3A4 inhibitors. Storage should occur below 25°C in a dry environment, protected from light.