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Overview
Ezetimibe is a selective cholesterol absorption inhibitor used in pharmaceutical synthesis. The core process involves chiral resolution and crystallization. Its molecular formula is C24H29NO3 with CAS number 154445-11-9.
Application
- Cardiovascular therapeutics for lowering LDL-C.
- Combination therapy with statins for hypercholesterolemia.
- Rare lipid disorder management like sitosterolemia.
Precautions
Contraindicated in active liver disease or pregnancy. Store below 25°C in dry, light-resistant containers. Avoid inhalation of dust during handling to prevent respiratory irritation.