Category:
Chiral Intermediates
CAS NO:
1501-27-5
Standard:
In-house Standards,
/
Ezetimibe first intermediate is a critical API precursor synthesized via selective chlorination of 4-chloro-2-fluorophenol followed by nucleophilic substitution. The core structure serves as the scaffold for the final cholesterol absorption inhibitor. Molecular Formula: C16H13ClFNO2; CAS No.: 159752-70-8.
Store under inert atmosphere at 2-8°C to prevent hydrolysis. Personnel must utilize PPE including nitrile gloves and respiratory protection due to potential irritancy. Not approved for direct clinical use; strictly regulated as an industrial chemical intermediate.